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The fix: inject on an empty stomach

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Both modifications sit in the region that IGF binding proteins recognise, and the functional consequence is a large loss of IGFBP affinity while type 1 IGF receptor binding is largely preserved

Ipamorelin is a 5-amino acid peptide that mimics ghrelin, the hunger hormone. It binds to ghrelin receptors (GHS-R) to stimulate a rapid spike in growth hormone release, without affecting cortisol or prolactin levels